Antagonistic effect of ursolic acid on Staphylococcal biofilms

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Synergistic effect of xylitol and ursolic acid combination on oral biofilms

OBJECTIVES This study was designed to evaluate the synergistic antibacterial effect of xylitol and ursolic acid (UA) against oral biofilms in vitro. MATERIALS AND METHODS S. mutans UA 159 (wild type), S. mutans KCOM 1207, KCOM 1128 and S. sobrinus ATCC 33478 were used. The susceptibility of S. mutans to UA and xylitol was evaluated using a broth microdilution method. Based on the results, com...

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Effect of biofilms on recalcitrance of staphylococcal joint infection to antibiotic treatment.

The pathogenesis of joint infections is not well understood. In particular, we do not know why these infections respond poorly to antibiotic treatment. Here we show that methicillin-resistant Staphylococcus aureus, a major cause of joint infections, forms exceptionally strong biofilmlike aggregates in human synovial fluid (SF), to an extent significantly exceeding biofilm formation observed in ...

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ژورنال

عنوان ژورنال: Veterinary World

سال: 2018

ISSN: 0972-8988,2231-0916

DOI: 10.14202/vetworld.2018.1440-1444